Depression is one of the most painful human experiences — a weight that can make even the smallest tasks feel impossible and the future feel unreachable. If you are walking through a season of darkness, you are not alone, and you are not forgotten. The Bible is filled with honest accounts of people who cried out to God from the depths of despair — and found Him faithful.
These 40+ Bible verses about depression are organized by theme to help you find comfort, strength, and hope exactly where you are.
Bible Verses About God Being Near to the Brokenhearted
One of the most comforting truths in all of Scripture is that God does not distance Himself from those who are suffering. He draws near. He sees. He cares. These verses speak directly to the heart that feels alone in its pain.
Psalm 34:18 “The LORD is close to the brokenhearted and saves those who are crushed in spirit.”
Psalm 147:3 “He heals the brokenhearted and binds up their wounds.”
Matthew 5:4 “Blessed are those who mourn, for they will be comforted.”
Isaiah 43:2 “When you pass through the waters, I will be with you; and when you pass through the rivers, they will not sweep over you. When you walk through the fire, you will not be burned; the flames will not set you ablaze.”
Zephaniah 3:17 “The LORD your God is with you, the Mighty Warrior who saves. He will take great delight in you; in his love he will no longer rebuke you, but will rejoice over you with singing.”
Bible Verses About Crying Out to God in Dark Times
Some of the most raw and honest prayers in the Bible come from people in the depths of despair. The Psalms in particular show us that it is not only acceptable to cry out to God from a place of anguish — it is an act of faith.
Psalm 22:24 “For he has not despised or scorned the suffering of the afflicted one; he has not hidden his face from him but has listened to his cry for help.”
Psalm 55:22 “Cast your cares on the LORD and he will sustain you; he will never let the righteous be shaken.”
Psalm 40:1–2 “I waited patiently for the LORD; he turned to me and heard my cry. He lifted me out of the slimy pit, out of the mud and mire; he set my feet on a rock and gave me a firm place to stand.”
Lamentations 3:55–57 “I called on your name, LORD, from the depths of the pit. You heard my plea: ‘Do not close your ears to my cry for relief.’ You came near when I called you, and you said, ‘Do not fear.'”
Psalm 18:6 “In my distress I called to the LORD; I cried to my God for help. From his temple he heard my voice; my cry came before him, into his ears.”
Bible Verses About Finding Strength When You Feel Weak
Depression often strips away our sense of strength and capacity. These verses remind us that God’s power is made perfect in weakness — and that He offers His strength to those who have none left of their own.
Isaiah 40:29–31 “He gives strength to the weary and increases the power of the weak. Even youths grow tired and weary, and young men stumble and fall; but those who hope in the LORD will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint.”
Philippians 4:13 “I can do all this through him who gives me strength.”
2 Corinthians 12:9 “But he said to me, ‘My grace is sufficient for you, for my power is made perfect in weakness.’ Therefore I will boast all the more gladly about my weaknesses, so that Christ’s power may rest on me.”
Psalm 46:1 “God is our refuge and strength, an ever-present help in trouble.”
Isaiah 41:10 “So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”
Bible Verses About Hope in the Midst of Depression
When depression makes the future look dark, Scripture points us to a hope that is not based on circumstances but on the unchanging character of God. These verses speak to the soul that is struggling to hold on.
Jeremiah 29:11 “‘For I know the plans I have for you,’ declares the LORD, ‘plans to prosper you and not to harm you, plans to give you hope and a future.'”
Romans 15:13 “May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.”
Lamentations 3:21–23 “Yet this I call to mind and therefore I have hope: Because of the LORD’s great love we are not consumed, for his compassions never fail. They are new every morning; great is your faithfulness.”
Psalm 42:11 “Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”
Romans 8:18 “I consider that our present sufferings are not worth comparing with the glory that will be revealed in us.”
Psalm 30:5 “Weeping may stay for the night, but rejoicing comes in the morning.”
Bible Verses About Peace and Anxiety
Depression and anxiety often travel together. These verses speak to the anxious mind and the restless heart, pointing to the peace that only God can give — a peace that surpasses all human understanding.
Philippians 4:6–7 “Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God. And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
John 14:27 “Peace I leave with you; my peace I give you. I do not give to you as the world gives. Do not let your hearts be troubled and do not be afraid.”
Isaiah 26:3 “You will keep in perfect peace those whose minds are steadfast, because they trust in you.”
Matthew 11:28–30 “Come to me, all you who are weary and burdened, and I will give you rest. Take my yoke upon you and learn from me, for I am gentle and humble in heart, and you will find rest for your souls. For my yoke is easy and my burden is light.”
1 Peter 5:7 “Cast all your anxiety on him because he cares for you.”
Bible Verses About God’s Presence When You Feel Alone
One of the cruelest lies depression tells is that you are completely alone. These verses speak the truth: God has not abandoned you, He has not forgotten you, and nothing — not even your darkest season — can separate you from His love.
Deuteronomy 31:8 “The LORD himself goes before you and will be with you; he will never leave you nor forsake you. Do not be afraid; do not be discouraged.”
Romans 8:38–39 “For I am convinced that neither death nor life, neither angels nor demons, neither the present nor the future, nor any powers, neither height nor depth, nor anything else in all creation, will be able to separate us from the love of God that is in Christ Jesus our Lord.”
Psalm 139:7–8 “Where can I go from your Spirit? Where can I flee from your presence? If I go up to the heavens, you are there; if I make my bed in the depths, you are there.”
Joshua 1:9 “Have I not commanded you? Be strong and courageous. Do not be afraid; do not be discouraged, for the LORD your God will be with you wherever you go.”
Psalm 23:4 “Even though I walk through the darkest valley, I will fear no evil, for you are with you; your rod and your staff, they comfort me.”
Bible Verses About Renewing Your Mind
Depression can distort the way we see ourselves, the world, and the future. Scripture calls us to actively renew our minds — to replace the lies depression whispers with the truth of God’s Word.
Romans 12:2 “Do not conform to the pattern of this world, but be transformed by the renewing of your mind. Then you will be able to test and approve what God’s will is — his good, pleasing and perfect will.”
2 Corinthians 10:5 “We demolish arguments and every pretension that sets itself up against the knowledge of God, and we take captive every thought to make it obedient to Christ.”
Psalm 119:114 “You are my refuge and my shield; I have put my hope in your word.”
Isaiah 55:8–9 “‘For my thoughts are not your thoughts, neither are your ways my ways,’ declares the LORD. ‘As the heavens are higher than the earth, so are my ways higher than your ways and my thoughts than your thoughts.'”
Colossians 3:2 “Set your minds on things above, not on earthly things.”
Bible Verses About God’s Faithfulness Through Suffering
Depression can make it feel as though God has forgotten His promises. These verses anchor us in the unchanging faithfulness of a God who has never once failed to keep His word.
Psalm 9:9–10 “The LORD is a refuge for the oppressed, a stronghold in times of trouble. Those who know your name trust in you, for you, LORD, have never forsaken those who seek you.”
2 Corinthians 4:8–9 “We are hard pressed on every side, but not crushed; perplexed, but not in despair; persecuted, but not abandoned; struck down, but not destroyed.”
Psalm 34:19 “The righteous person may have many troubles, but the LORD delivers him from them all.”
James 1:2–4 “Consider it pure joy, my brothers and sisters, whenever you face trials of many kinds, because you know that the testing of your faith produces perseverance. Let perseverance finish its work so that you may be mature and complete, not lacking anything.”
Nahum 1:7 “The LORD is good, a refuge in times of trouble. He cares for those who trust in him.”
Bible Verses About God Restoring and Healing
The God of Scripture is a God of restoration. He specializes in bringing beauty out of ashes, joy out of mourning, and life out of what feels like complete darkness.
Joel 2:25 “I will repay you for the years the locusts have eaten — the great locust and the locust swarm — my great army that I sent among you.”
Psalm 51:12 “Restore to me the joy of your salvation and grant me a willing spirit, to sustain me.”
Isaiah 61:3 “And provide for those who grieve in Zion — to bestow on them a crown of beauty instead of ashes, the oil of joy instead of mourning, and a garment of praise instead of a spirit of despair.”
Revelation 21:4 “He will wipe every tear from their eyes. There will be no more death or mourning or crying or pain, for the old order of things has passed away.”
Psalm 71:20–21 “Though you have made me see troubles, many and bitter, you will restore my life again; from the depths of the earth you will again bring me up. You will increase my honor and comfort me once more.”
If you are struggling with depression, please know that reaching out for help — to God, to trusted people in your life, and to a mental health professional — is not a sign of weakness. It is an act of courage and wisdom. The Bible’s heroes — David, Elijah, Jeremiah, Job — all walked through deep valleys of despair. God met every one of them there, and He will meet you too. You can also read bible verse about mental health.
If you are in crisis, please contact the 988 Suicide & Crisis Lifeline by calling or texting 988 (US). You do not have to face this alone.
Searching for more Scripture to guide your faith? Explore our full Bible Verses collection organized by topic, go deeper with our Bible Lessons for context and study, or put these verses into practice with our daily devotional series. Need prayer support? Visit our guided prayers for every season of life. Download the FaithTime app to receive personalized Bible verses and reflections daily.
